Working toward a life less interrupted for people with IC/BPS.

Living with interstitial cystitis and bladder pain syndrome (IC/BPS) can be debilitating, but Ironwood is sponsoring a clinical research study of a new potential treatment that could offer relief. The IC/BPS Clinical Study will evaluate an investigational, foam-based drug designed to inhibit pain receptors in the colon, which may modify pain in the bladder.

Many of the 4 to 12 million people in the U.S. with IC/BPS may be interested in a new option for pain management as they have been unable to find relief from the discomfort and life interruption associated with the disease. This is why we’re conducting the IC/BPS Clinical Study.

What is IC/BPS?

IC/BPS is a chronic condition with symptoms of increased urinary urgency and frequency, nighttime urination, bladder pressure and severe pelvic pain. Pain and symptoms experienced due to IC/BPS can make daily life difficult and painful and may be so severe that they can negatively impact a person’s quality of life.

In an effort to develop a safe, dedicated, potential pain management option to relieve IC/BPS pain, Ironwood is conducting a phase 2 clinical trial of a novel, rectally administered foam. The study drug is designed to utilize the shared nerve pathways between the colon and bladder to modify pain signals in the colon, which might also relieve bladder pain associated with IC/BPS.

IC/BPS Clinical Study at a Glance

  • Participants: 300
  • Duration: Up to 21 weeks (including Screening Period)
  • Administration: Rectal
  • Study Groups: Three groups (two groups receiving doses of the investigational drug and one group receiving placebo)

To participate in this study, you must meet these criteria*:

  • Adult between the ages of 18 and 70
  • Suffering for six months or more from chronic bladder pain associated with filling the bladder
  • Experiencing at least one of the following urinary symptoms related to IC/BPS for six months or more:
    • Nighttime urination, two or more times per night
    • Frequent urination during the daytime, more than eight times per day
    • Urination urgency

*Other criteria will apply.

While participating in the study, you’ll receive one of two doses of the investigational drug or a matching placebo, study-related care and monitoring of your IC/BPS symptoms and compensation for travel and expenses related to study participation, if needed.

To learn more and find out if you may be eligible,

please visit icbpsclinicalstudy.com

Study Locations:

(*indicates a center will open soon)

Alabama Locations

  • Mobile, Alabama, United States, 36608*

Arizona Locations

  • Scottsdale, Arizona, United States, 85259*
  • Tucson, Arizona, United States, 85715 – Urological Associates of Southern Arizona
    Contact: J Simpson jsimpson@arizonauro.com

California Locations

  • Los Angeles, California, United States, 90017 – American Institute of Research
    Contact: N Aguillon naguillon@airesearch.us
  • Murrieta, California, United States, 92562 –  Tri Valley Urology Medical Group
    Contact: A Deeds anita@trivalleyurology.com
  • Orange, California, United States, 92868 – UCI Health
    Contact: P Linh Huynh plhuynh@hs.uci.edu
  • San Diego, California, United States, 92130*
  • Vacaville, California, United States, 95688*

District of Columbia Locations

  • Washington, District of Columbia, United States, 20010*

Florida Locations

Georgia Locations

  • Cartersville, Georgia, United States, 30120*

Idaho Locations

  • Idaho Falls, Idaho, United States, 83404 – Leavitt Clinical Research
    Contact: L Carranza liz@drleavitt.net

Indiana Locations

Louisiana Locations

  • New Orleans, Louisiana, United States, 70121 – Ochsner Clinic Foundation
    Contact: R Graham rgraham@ochsner.org

Massachusetts Locations

  • Watertown, Massachusetts, United States, 02472 – Bay State Clinical Trials
    Contact:  T Lafleur tmlbsct@gmail.com

Michigan Locations

Nebraska Locations

  • Omaha, Nebraska, United States, 68114 – Quality Clinical Research
    Contact: J Larsen jenny@qcromaha.com

New Jersey Locations

  • Hackensack, New Jersey, United States, 07601*

New Mexico Locations

  • Albuquerque, New Mexico, United States, 87106 – New Mexico Clinical Research and Osteoporosis Center
    Contact: T Salazar TSalazar@nmbonecare.com

New York Locations

  • Albany, New York, United States, 12208 – Urological Institute of Northeast New York
    Contact: L Davey amcurologyresearch@mail.amc.edu
  • Garden City, New York, United States, 11530 – Accumed Research Associates
    Contact: H Delmauro heather.accumedresearch@gmail.com
  • New Hyde Park, New York, United States, 11042*
  • New York, New York, United States, 10032*

North Carolina Locations

  • Winston-Salem, North Carolina, United States, 27103*

Ohio Locations

  • Gahanna, Ohio, United States, 43230*
  • Mayfield Heights, Ohio, United States, 44124*
  • Zanesville, Ohio, United States, 43701 – Genesis Healthcare System
    Contact: C Griffin Cgriffin2@genesishcs.org

Pennsylvania Locations

  • Bala-Cynwyd, Pennsylvania, United States, 19004 – MidLantic Urology
    Contact: K Liberatore kliberatore@midlanticurology.com
  • Reading, Pennsylvania, United States, 19611*

South Carolina Locations

  • Charleston, South Carolina, United States, 29425*

South Dakota Locations

  • Sioux Falls, South Dakota, United States, 57105*

Tennessee Locations

Texas Locations

  • Dallas, Texas, United States, 75204*
  • Houston, Texas, United States, 77096*
  • Pearland, Texas, United States, 77584 – Advances In Health Inc
    Contact: E Loya elizabethloya@aihresearch.com

Utah Locations

  • Salt Lake City, Utah, United States, 84124 – Highland Clinical Research
    Contact: S Mueller saramueller2@outlook.com

Virginia Locations

  • Vienna, Virginia, United States, 22182 – The Chronic Pelvic Pain Center
    Contact: C Prieston case.cppc@gmail.com

Washington Locations

  • Seattle, Washington, United States, 98105 – Seattle Clinical Research Center
    Contact: S Emerald semerald@seattlecrc.com

To learn more and find out if you may be eligible,

please visit icbpsclinicalstudy.com