If symptoms of interstitial cystitis or bladder pain - like urinary problems or discomfort - impact everyday activities, you may qualify for a study. The OAG1050 study is testing an investigational medication that is designed to help alleviate the symptoms of IC/BPS. The investigational medication is a tablet taken once daily before bed. You [...]
For a few years, the urologic community has been abuzz with news of a preventative UTI vaccine called Uromune (MV140). The vaccine, which has been utilized in 26 countries, is growing in use throughout North America. It was recently approved in Mexico and has been studied closely in Canada as well.(1, 2) The North [...]
Working toward a life less interrupted for people with IC/BPS. Living with interstitial cystitis and bladder pain syndrome (IC/BPS) can be debilitating, but Ironwood is sponsoring a clinical research study of a new potential treatment that could offer relief. The IC/BPS Clinical Study will evaluate an investigational, foam-based drug designed to inhibit pain receptors [...]
Researchers at the Emory Eye Center (Atlanta, GA) studying retinal eye disease have made another remarkable finding, that some IC/BPS patients using pentosan polysulfate (PPS, Elmiron®) are struggling with inflammatory bowel disease, some so severe that colectomy (removal of a section of the colon) was required.(1) Elmiron® is the only FDA approved medication for [...]
New Transcranial Stimulation Study in Southern California Seeks IC/BPS Patients With the now universal acceptance that many IC/BPS patients struggle with widespread pain (myself included), the central nervous system has become a new therapeutic target. Understanding how the brain and nerves influence pelvic pain and muscle health is the focus of Dr. Jason Kutch's [...]
For more than 30 years, newly diagnosed patients with IC/BPS were given bladder medications with little, if any, success. Why? Researchers and clinicians believed, at that time, that IC was an incurable bladder disease. Today, that perception has changed dramatically. Our updated 2022 AUA Guidelines for IC/BPS very clearly state that no active "disease" [...]
This Shouldn't Be Happening! Despite millions of dollars invested in research that has proven that IC/BPS is a legitimate pelvic pain condition, women continue to feel disregarded and ignored by their physicians. In fact, a new study from Vanderbilt University and the NIH found that while men with IC/BPS often felt supported by their [...]
For interstitial cystitis and overactive bladder patients struggling with intense urinary frequency and urgency, physicians often prescribe anticholinergic medications such as Amitryptiline (Elavil), imipramine (Tofranil) or Nortryptiline (Pamelor), Oxybutynin (Ditropan, Oytrol) or Tolteradine (Detrol). Unfortunately, their use has now been linked to cognitive decline and dementia in some patients who use it daily for long [...]
We were heartbroken to learn that Rosiptor (AQX-1125), once believed to be a promising new therapy for interstitial cystitis and bladder pain syndrome, has failed to demonstrate success in their latest clinical trial, the Phase 3 LEADERSHIP 301 study. In a press conference, David Main, CEO of Aquinox Pharmaceuticals, said “This is a disappointing result for [...]
