///Hunner’s Lesion Triamcinolone Treatment Shows Effectiveness and Long Term Durability

Hunner’s Lesion Triamcinolone Treatment Shows Effectiveness and Long Term Durability

If you struggle with Hunner’s lesions (aka Hunne’s ulcers), the odds are that you’ve tried a variety of bladder treatments with little effect. Why is Elmiron and/or DMSO ineffective for Hunner’s lesions? Because they don’t treat the lesion directly. The American Urology Association recommends lesion directed therapy: fulguration, laser therapy and/or triamcinolone injection into the lesion. The challenge with the first two (and any heat treatment) is that it can leave scarring which can then reduce the ability of the bladder to expand (i.e. bladder capacity). In contrast, simply injecting the lesion with a simple steroid solution is just as effective but far less traumatic on the patient and the bladder.

Researchers at the Hofstra Northwell School of Medicine (New York) studied the effectiveness of low dose triamcinolone injection for HL treatment. A total of 36 patients received this treatment at their facility between 2001 and 2015. 78% were female and 22% were mail. Of these, 72% received just one set of infections. 22% received 2 sets of injections and 5.5% received 3 or more injections with triamcinolone.  The average time between injections was just less than a year.

Their reduction in pain was remarkable. Prior to treatment, their pain scores were 8.3 using the Likert pain scale. One month after treatment their pain scores reduced to 3.8. Nighttime frequency reduced from 7.5 to 5.1 after treatment.  Researchers conclude that triamcinolone treatment of Hunner’s lesions is effective and durable, with low morbidity. It can be performed on an outpatient basis.

Of course, we continue to await the results of the latest LiRIS study for the treatment of Hunner’s lesions. In previous studies, the LiRIS medical device was found to reduce the size, quantity and/or completely resolve lesions with a simple two week treatment. More on that to come!

Read more about the Hunner’s lesion treatment here! 


  1. Funaro MG, et al. Endoscopic Injection of Low Dose Triamcinolone: a Simple, Minimally Invasive and Effective Therapy for Interstitial Cystitis with Hunner Lesions. Urology 2018 May 18
  2. Guttman Krater C. Device efficacious for treating IC with Hunner’s lesions. Urology Times. October 1, 2016
By |2018-05-29T21:49:04+00:00May 29th, 2018|Latest Research, Research|Comments Off on Hunner’s Lesion Triamcinolone Treatment Shows Effectiveness and Long Term Durability

About the Author:

My Google Profile+ Jill Heidi Osborne is the president and founder of the Interstitial Cystitis Network, a health education company dedicated to interstitial cystitis, bladder pain syndrome and other pelvic pain disorders. As the editor and lead author of the ICN and the IC Optimist magazine, Jill is proud of the academic recognition that her website has achieved. The University of London rated the ICN as the top IC website for accuracy, credibility, readability and quality. (Int Urogynecol J - April 2013). Harvard Medical School rated both Medscape and the ICN as the top two websites dedicated to IC. (Urology - Sept 11). Jill currently serves on the Congressionally Directed Medical Research Panel (US Army) where she collaborates with researchers to evaluate new IC research studies for possible funding. Jill has conducted and/or collaborates on a variety of IC research studies on new therapeutics, pain care, sexuality, the use of medical marijuana, menopause and the cost of treatments, shining a light on issues that influence patient quality of life. An IC support group leader and national spokesperson for the past 20 years, she has represented the IC community on radio, TV shows, at medical conferences. She has written hundreds of articles on IC and its related conditions. With a Bachelors Degree in Pharmacology and a Masters in Psychology, Jill was named Presidential Management Intern (aka Fellowship) while in graduate school. (She was unable to earn her PhD due to the onset of her IC.) She spends the majority of her time providing WELLNESS COACHING for patients in need and developing new, internet based educational and support tools for IC patients, including the “Living with IC” video series currently on YouTube and the ICN Food List smartphone app! Jill was diagnosed with IC at the age of 32 but first showed symptoms at the age of 12.