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You Are Here: Interstitial Cystitis Network : ICN Research Library : Elmiron Studies
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Misleading report of massive bleeding in a patient taking pentosan polysulfate.Parsons CL.
Arch Intern Med. 2003 Jan 13;163(1):119; authors reply 119-20. No abstract
available.
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Effect of pentosan polysulfate therapy on intravesical potassium sensitivity.
Parsons CL, Forrest J, Nickel JC, Evans R, Lloyd LK, Barkin J, Mosbaugh PG,Kaufman DM, Hernandez-Graulau JM, Atkinson L, Albrecht D.
Urology. 2002 Mar;59(3):329-33.
- Sodium pentosan polysulfate reduces urothelial responses to inflammatory stimulivia an indirect mechanism.
Sadhukhan PC, Tchetgen MB, Rackley RR, Vasavada SP, Liou L, Bandyopadhyay SK.
J Urol. 2002 Jul;168(1):289-92.
- Massive bleeding on a bladder protectant: a case report of pentosan polysulfate sodium-induced coagulopathy.
Gill S, Naiman SC, Jamal A, Vickars LM.
Arch Intern Med. 2002 Jul 22;162(14):1644-5.
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Lysosomal-storage disorder induced by elmiron following 90-days gavage
administration in rats and mice.
Nyska A, Nold JB, Johnson JD, Abdo K.
Toxicol Pathol. 2002 Mar-Apr;30(2):178-87.
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Psychometric validation of the O'leary-Sant interstitial cystitis symptom index
in a clinical trial of pentosan polysulfate sodium.
Lubeck DP, Whitmore K, Sant GR, Alvarez-Horine S, Lai C.
Urology. 2001 Jun;57(6 Suppl 1):62-66.
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Safety and efficacy of up to 900 mg/day polysulfate sodium (elmiron) in patients with interstitial cystitis.
Nickel JC, Forrest J, Barkin J, Payne C, Mosbaugh P.
Urology. 2001 Jun;57(6 Suppl 1):122-123. No Abstract available.
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NEW STUDY CONFIRMS PENTOSAN POLYSULFATE SODIUM IS HIGHLY EFFECTIVE IN TREATING INTERSTITIAL CYSTITIS AND SUGGESTS INCREASED SYMPTOM RELIEF WITH CONTINUED THERAPY
Alza Corporation
ANAHEIM, Ca., June 3, 2001
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Studies on the structural variations of pentosan polysulfate sodium (NaPPS) from different sources by capillary electrophoresis.
Degenhardt M, Ghosh P, Watzig H.
Arch Pharm (Weinheim). 2001 Jan;334(1):27-9.
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PENTOSANPOLYSULFATE INHIBITS MAST CELL HISTAMINE SECRETION AND INTRACELLULAR
CALCIUM ION LEVELS: AN ALTERNATIVE EXPLANATION OF ITS BENEFICIAL EFFECT IN
INTERSTITIAL CYSTITIS. Chiang G, Patra P, Letourneau R, Jeudy S, Boucher W, Green M, Sant GR,
Theoharides TC.,
J Urol. 2000 Dec;164(6):2119-2125.
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Pentosan polysulfate therapy for chronic nonbacterial prostatitis (chronic
pelvic pain syndrome category IIIA): a prospective multicenter clinical trial.
Nickel JC, Johnston B, Downey J, Barkin J, Pommerville P, Gregoire M, Ramsey E.
Urology. 2000 Sep 1;56(3):413-7.
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Interstitial cystitis: a retrospective analysis of treatment with pentosan polysulfate and follow-up patient survey. Waters MG, Suleskey JF, Finkelstein LJ, Van Overbeke ME, Zizza VJ, Stommel M.
J Am Osteopath Assoc 2000 Mar;100(3 Suppl):S13-8
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Elevated urinary norepinephrine in interstitial cystitis.
Stein PC, Torri A, Parsons CL
Urology. 1999 Jun;53(6):1140-3.
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Potassium leak test predicts outcome in interstitial cystitis.
Teichman JM, Nielsen-Omeis BJ
J Urol 1999 Jun;161(6):1791-4; discussion 1794-6
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Long-term use of pentosan polysulfate for interstitial cystitis.
Evans RJ
Urology. 1999 Apr;53(4):863. No abstract available.
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Natural history of interstitial cystitis in 274 patients receiving sulfated polysaccharide therapy.
Ho NJ, Koziol JA, Parsons CL, Barlow W, Weiss NS;
Urology. 1999 Jun;53(6):1133-9.
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Pentosanpolysulphate for interstitial cystitis.
Barrington JW, Stephenson TP
Int Urogynecol J Pelvic Floor Dysfunct 1997;8(5):293-5
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Long-term experience with pentosanpolysulfate in interstitial
cystitis.
Jepsen JV, Sall M, Rhodes PR, Schmidt D, Messing E, Bruskewitz RC
Urology 1998 Mar;51(3):381-7
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Analysis of long-term Elmiron therapy for interstitial cystitis.
Hanno PM - Urology 49(5A), 93-99 (1997)
- Epithelial coating techniques in the treatment of interstitial cystitis.
Parsons CL - Urology 49(5A), 100-104 (1997)
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A placebo-controlled study of intravesical pentosanpolysulphate for the treatment of interstitial cystitis.
Bade JJ - Br J Urol 79(2), 168-171 (1997)
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Potassium sensitivity test.
Parsons, CL - Tech Urol 2(3), 171-173 (1996)
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The therapeutic role of sulfated polysaccharides in the urinary bladder.
Parsons, CL - Urologic Clinics of North America, Vol. 21,No.1, Feb 1994,20-100
Other Suggested Readings
Intravesical Therapies For Interstitial cystitis.
Dennis R. La Rock & Grannum R. Sant
Interstitial Cystitis: Grannum R. Sant
Philadelphia: Lippencott-Raven, 1997: Chapt: 31
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