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IC Animal Studies

• Effects of methoctramine on bladder overactivity in a rat model. ztrk H, et al. Urology. 2003 Mar;61(3):671-6.

• Feline Interstitial Cystitis Results in Mechanical Hypersensitivity and Altered ATP Release from Bladder Urothelium. Birder LA, et al. Am J Physiol Renal Physiol. 2003 May 20 [Epub ahead of print]

• Development and Application of Chymase Inhibitors: Development of the Chymase Inhibitor as an Anti-Tissue-Remodeling Drug: Myocardial Infarction and Some Other Possibilities. Sukenaga Y, Kamoshita K, Takai S, Miyazaki M. Jpn J Pharmacol. 2002;90(3):218-222.

• Intravesical liposome administration-a novel treatment for hyperactive bladder in the rat. Fraser MO, et al. Urology. 2003 Mar;61(3):656-63.

• Indomethacin-induced morphologic changes in the rat urinary bladder epithelium. Cetinel S, Cetinel B, Ercan F, Hrda C, San T. Urology. 2003 Jan;61(1):236-42.

• Norepinephrine content and adrenoceptor function in the bladder of cats with feline interstitial cystitis. Buffington CA, Teng B, Somogyi GT. J Urol. 2002 Apr;167(4):1876-80.

• Lysosomal-storage disorder induced by elmiron following 90-days gavage administration in rats and mice. Nyska A, Nold JB, Johnson JD, Abdo K. Toxicol Pathol. 2002 Mar-Apr;30(2):178-87.

• Norepinephrine content and adrenoceptor function in the bladder of cats with feline interstitial cystitis. Buffington CA, Teng B, Somogyi GT. J Urol. 2002 Apr;167(4):1876-80.

• A portuguese isolate of Borrelia lusitaniae induces disease in C3H/HeN mice. Zeidner NS, Nuncio MS, Schneider BS, Gern L, Piesman J, Brandao O, Filipe AR. J Med Microbiol. 2001 Dec;50(12):1055-60.

• In vivo models of interstitial cystitis. Westropp JL, Buffington CA. J Urol. 2002 Feb;167(2 Pt 1):694-702. Review.

• Estrogenic regulation of HSP90 kD synthesis in rat urinary bladder. Stein PC, Ha TJ, Parsons CL. Urol Res. 2001 Oct;29(5):338-44.

• Estrous influences on micturition thresholds of the female rat before and after bladder inflammation. Johnson OL, Berkley KJ. Am J Physiol Regul Integr Comp Physiol. 2002 Jan;282(1):R289-94.

• Morphological examination of the effects of defibrotide on experimentally induced bladder injury and its relation to interstitial cystitis. Aydin H, Ercan F, Cetinel S, San T. Urol Res. 2001 Aug;29(4):263-71.

• Intravesical ethanol as quantitative measure of bladder hyperpermeability. Monga M, Percival C, Zupkas P. J Endourol. 2001 Aug;15(6):641-4.

• Mast cell regulation of inflammation and gene-expression during antigen-induced bladder inflammation in the mouse. Saban R, Saban MR, Nguyen NB, Hammond TG, Wershil BK. Physiol Genomics. 2001 Aug 8 [epub ahead of print]

• Visceral pain in humans: lessons from animals. Buffington CA. Curr Pain Headache Rep. 2001 Feb;5(1):44-51. Review.

• Basic science research on the urinary bladder and interstitial cystitis: new genetic approaches. Liebert M. Urology. 2001 Jun;57(6 Suppl 1):7-8.

• Increased plasma norepinephrine concentration in cats with interstitial cystitis. Buffington CA, Pacak K. J Urol. 2001 Jun;165(6 Pt 1):2051-4.

• A reliable, nondestructive animal model for interstitial cystitis: intravesical low-dose protamine sulfate combined with physiological concentrations of potassium chloride. Fraser MO, Chuang Y, Lavelle JP, Yoshimura N, de Groat WC, Chancellor MB Urology. 2001 Jun;57(6 Suppl 1):112. No Abstract available.

• Effects of resiniferatoxin on the neurogenic component of feline interstitial cystitis. March P, Teng B, Westropp J, Buffington T. Urology. 2001 Jun;57(6 Suppl 1):114. No Abstract available.

• Cell relationship in a wistar rat model of spontaneous prostatitis. Keith IM, Jin J, Neal Jr D, Teunissen BD, Moon TD. J Urol.2001 Jul;166(1):323-8.

• Increased plasma norepinephrine concentrations in cats with interstitial cystitis. Buffington T, Pacak K. Urology. 2001 Jun;57(6 Suppl 1):102. No Abstract available.

• Automated noninvasive measurement of cyclophosphamide-induced changes in murine voiding frequency and volume. Wood R, Eichel L, Messing EM, Schwarz E. J Urol. 2001 Feb;165(2):653-9.

• Urothelial pathophysiological changes in feline interstitial cystitis: a human model. Lavelle JP, Meyers SA, Ruiz WG, Buffington CA, Zeidel ML, Apodaca G. Am J Physiol Renal Physiol 2000 Apr;278(4):F540-F553

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