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Revision: April 5, 2004
Jill Osborne

Created: June 1999
Jill Osborne


You are here: IC Network > Patient Handbook > Pain Management - Understanding IC Pain

Pain Management and IC

Understanding IC Pain

There are three types of pain carried by different parts of our nervous system. People feel different sensations and symptoms with each.

Somatic pain starts in the skin, muscles and bone and is usually localized. Everyone has had somatic pain. When you cut yourself, it hurts intensely and then a few minutes later, it doesn't hurt as much. We don't suffer for days and days with this pain. We don't lose our emotional composure. This type of pain resolves quickly.

Visceral pain is the most common pain found in IC patients. The pain is caused by inflammation, distention and/or increased amounts of pressure. It is not localized and produces stronger autonomic and affective responses.

Visceral pain has a more agonizing quality. It is carried to a different part of the brain than the somatic, the part of the brain that deals with emotions. So people with visceral pain have emotional content.. they get more upset and may cry often. Why? Emotions are a physical quality of the pain. It doesn't mean that the patient is emotionally weak or having a breakdown. It just means that a different part of the brain is being stimulated.

Neuropathic pain is usually caused by a degeneration of the nervous system, i.e. that the nerves have damaged in some way. It often feels like burning or shooting pain. Some patients describe it as electrical shocks. It can be a harder pain to treat.

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The Pain of IC

In IC, the bladder is inflamed and, at times, severely irritated. Why? We're not sure. It appears that the nerves within the bladder have become hypersensitized, perhaps by infection, urinary toxins, histamine or other substances which can irritate the bladder. Hyperalgia subsequently develops, in which the bladder becomes more sensitized and responds with high levels of pain, even if the source of the pain is mild.

If the patient receives no treatment for pain, the repeated pain signals sent from the bladder to the spine may cause changes in the dorsal horn of the spinal cord, which can then perpetuate the pain signals to the brain independently of the bladder. This is called central sensitization and could explain why some IC patients may still experience what feels like bladder pain even after their bladder is removed. It is also believed that persistent irritation and stimulation may cause the normally silent nerves of the bladder, the hypogastric and lumbar splanchnic nerves, to become activated (1).

When IC patients speak of their pain, they often describe it in many different ways, including: pressure, heat, electrical currents, razor blades or ground glass. Many IC patients also describe their pain as being referred to their back, vagina, rectum, perineum or lower extremities.

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Recommended Reading

The Interstitial Cystitis Survival Guide, by Robert Moldwin, MD.
Special Report on Pain by the San Francisco Chronicle

References

(1) Brookoff D. The causes and Treatment of Pain in Interstitial Cystitis, in G. Sant (Ed.), Interstitial Cystitis. Philadelphia: Lipincott-Raven Publishers, 1997; 177-192



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