Does Prozac irritate your bladder? - Interstitial Cystitis Network Support Forum

peiti · 08-09-2004, 05:57 AM

I am prescribed 20mg Prozac a day for my depression. I took it for two days. It irritated my bladder a little bit. Does this happen to you as well?

RedLione · 08-09-2004, 07:43 AM

I have yet to find an antidepressant that does not irritate my bladder. My doctor prescribes them for sleep, but I can't tolerate them. The only one I haven't tried yet is Wellbutrin.

**Kathi** · 08-09-2004, 12:31 PM

I take 20 mg of Prozac & find it helps me alot. If I forget it I usually hurt by noon time. Everyone is different. Hugs, Kathi

vm · 08-09-2004, 01:09 PM

I take Lexapro and it actually helps my bladder. I wasn't expecting that at all - but it's been a nice unexpected side effect.

lulu5 · 08-09-2004, 05:02 PM

I take 20 mg of Prozac twice a day, and my pain is sooooo much better on it! Everyone is so different though. I did take Wellbutrin at one time, and I think it may have been the trigger for my IC to start (symptoms began two days later), so I stay away from that one completely, but Prozac has been a Godsend!

Melanie · 08-10-2004, 08:45 AM

Yes, Prozac irritated my bladder. Effexor was another bad one for my IC.

Wellbutrin worked great for me. But usually it's a process of trial and error to find the right pill that helps depression but doesn't hurt IC.

JOJO · 08-13-2004, 07:59 PM

Hi
Prozac hasnt bothered my bladder. I am no expert but before you give up on the drug,see if other things are going on, like where you are in menstral cycle,what have you eaten. Sometimes I think some of us dont take this into consideration, and we assume right away something new is the culprit. When I ovulate I know its flare up time for me. So you might want to hang in there,we are all different-JOJO Good Luck

RedLione · 08-14-2004, 02:51 AM

You're right, of course, JoJo that it could be many things. I can skip my antidepressant just one night and have the pain go away, or be okay on it and increase my dose and have a flareup. I've watched the pattern for years and I'm sure that's it. No menstrual cycles, so it's not that. I have learned from posts on another part of this site that antihistimines help, and they certainly allow me to tolerate the antidepressant I need to help me sleep. I guess it only works if you have "mast cells," and that must be my case because benadryl works for me.

JOJO · 08-14-2004, 05:03 PM

Well than nobody knows their body better than ourselves. You know your IC.I was trying to make a suggestion, I hope you werent angry. I wish you luck in finding what works for you. Take Care-JOJO

janetm · 08-15-2004, 12:14 PM

I have tried prozac twice. Each time it has irrirtated my baldder very much. It takes a couple of days for the effect to build up.

RedLione · 08-16-2004, 03:27 AM

Oh, JoJo, I wasn't offended. I come here looking for suggestions, and I also hope that some of the ones I make help others. So far I've gotten a lot of help here.

ICLori · 08-16-2004, 10:52 AM

Haven't tried Prozac lately but Effexor, the tricyclics and the pink tablet of Celexa (but not the white tablets) irritate my bladder horribly.

Blessings, Lori