Can my body become resistant

[Bea]

to imipramine.. do you need more after some time..

I am eating well.. and still no change..

I was doing so good

[Katrina]

I don't know for sure I would think so.....you can research online.

Dosage
Depression:
The dosage should be individualized according to the requirements of each patient. Treatment should be initiated at the lowest recommended dose and increased gradually noting carefully the clinical response and any evidence of intolerance, particularly when treating elderly and adolescent patients. It should be kept in mind that a lag in therapeutic response usually occurs at the onset of therapy, lasting from several days to a few weeks. Increasing the dosage does not normally shorten this latent period and may increase the incidence of side effects.

Adults:
Initial dosage:
25 mg 3 times daily. This should be increased gradually as required and tolerated up to 150 mg/day. Dosages over 200 mg/day are not recommended. In severely ill, hospitalized patients, initially 100 mg/day in divided doses, gradually increasing to 200 mg/day, if required. If no significant response is observed after 3 weeks, dosage may be increased up to 250 to 300 mg/day.

Elderly and debilitated patients:
30 to 40 mg/day, in divided doses, gradually increasing dosage if necessary, and tolerated; it is generally not necessary to exceed 100 mg/day.

Maintenance dosage:
Dosage during maintenance therapy should be kept at the lowest effective level. Medication should be continued for the expected duration of the depressive episode in order to minimize the possibility of relapse following clinical improvement.

When a maintenance dosage has been established as described above, imipramine may be administered in a single daily dose at bedtime, provided such a dosage regimen is well tolerated.

http://www.mentalhealth.com/drug/p30-t03.html

[mayray518]

My body became resistant to DMSO but I have been on elavil for 6 years and have gotten down to 5 mg and still feel great. I think I have IC under control now if I continue the elavil.

[Teri]

Bea~yes your body can. I am a hard patient to treat because I suffer from what my shrink calls "drug burn-out". It will work for me for a couple of years and then, almost like over night, it stops and I have to be put on something different
I'm going thru it again right now and just don't know where I'm going to find the strength to take care of it~

wishing you the very best~