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Go Back   Interstitial Cystitis Network Support Forum > Treatments For Mild Interstitial Cystitis (frequency/urgency) > Antidepressants (Elavil, etc.)
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Old 11-12-2009, 05:59 AM   #1
wenben
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Join Date: Feb 2009
Posts: 6
What to take for depression??

Hi,
What can we take for depression if SSRI's cause flares? I was on Elavil and loved it for the pain relief, but developed rapid heartbeat. Then tried Nortriptyline and that wired me, could not sleep. I don't know what to try next for the pain relief and the mild depression that seems to follow me with this disease. I have migraines too, so never know what the day will bring

Any ideas please please share.....thank you.
Wen
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Old 11-12-2009, 06:08 AM   #2
leelee88
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I take activan.. My anxiety was REALLY bad though to the point I was have major panic attacks... Also I recently started Prozac, BUT Had to start on the lowest dose possible which comes in the form of a liquid..And then had to dilute that! So far I am not having any side effects from it..
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Ronda

ONE Second, ONE Bite, ONE Breath, ONE Pill, ONE Minute, ONE Teardrop, ONE Hour, ONE Sip.. ONE DAY! I will Prevail from this disease! IC Hoping for a Cure!


Link to Patient Handbook:
http://www.ic-network.com/handbook/

Diet Reference Sheet:
http://www.ic-network.com/diet/icndi...tsheet0909.pdf

Meds For IC: Lyrica-25mg Glucosamine-500 MSM-500mg, Prosed Ds -When Flaring

Other Meds: Levlite- Continious Birtcontrol, Micardis-40mg for High Blood Pressure

Meds I have Tried:
Topamax,Tofranil, Elmiron, Atarax, Cymbalta, Elavil, Enablex, Detral La, Prydium.
Lexapro< Bad reaction to this med!
Intstills, could not continue them due to some kind of reaction after 3rd instill. Tasted the lidocaine in my mouth, tongue and lips went numb then went into what seemed like a panic attack. Shaking, racing heart, tingling face/head, blood pressure shot up..

Dx With IC in Nov 2006 with Hydro/Cysto
Hydro/Cysto Caused Bladder to Rupture.

Other Dxs-Vulvodynia,Fibro, Endo, IBS, HPV, Migraines, Spastic Colon, Mild Dysplasia.



ICN Volunteers are not medical authorities nor do we offer medical advice. In all cases, we strongly encourage you to discuss your medical treatment with your personal medical care provider. Only they can, and should, give medical recommendations to you.
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Old 11-12-2009, 07:01 AM   #3
wenben
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Thanks for the reply Rhonda. I take the ativan at night for sleep. Maybe you are right in taking the Prozac in very small doses. It would be great to have one pill for pain and depression etc....nice to dream.
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Old 11-12-2009, 07:07 AM   #4
vm
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Not all of us flare from SSRIs - mine actually helps my symptoms.
__________________
Kim

Diagnosed August 2001

Current IC meds: Elmiron (since 2001), Levaquin (one pill after intercourse to prevent UTIs), Lexapro (since 2003 for depression & anxiety, but also helps my IC)


Past IC meds: Amitriptyline (Elavil), Hydroxyzine (Vistaril), Detrol LA (They all helped, but I was able to discontinue them.)

My IC story: http://www.ic-network.com/patientstories/kim.html It's very outdated now. I've been virtually symptom free and able to eat & drink whatever I'd like for several years now.

*****************************

“We who lived in concentration camps can remember the men who walked through the huts comforting others, giving away their last piece of bread. They may have been few in number, but they offer sufficient proof that everything can be taken from a man but one thing: the last of the human freedoms -- to choose one's attitude in any given set of circumstances, to choose one's own way.” ~ Viktor Frankl

“You cannot control what happens to you, but you can control your attitude toward what happens to you, and in that, you will be mastering change rather than allowing it to master you.” ~ Brian Tracy
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Old 11-12-2009, 07:38 AM   #5
wenben
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Hey Kim,
Would you mind telling me what med you are or were on that helped? Do SSRI's help with pain too? I have been through a few meds and am a little scared to try something although desparate at the same time argh.
Wen
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Old 11-12-2009, 07:57 AM   #6
vm
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The one I take is Lexapro. I have heard others say it made their IC worse, so it seems that like so many other things with this disease - it's individual. *sigh* I am not sure if it would have the same effect for you, but suppose that it could. Lots of others here have taken SSRIs for mental health reasons and they have not adversely affected their bladders, so there isn't a guarantee that they WILL cause flares. Which is very good news.

I started taking Lexapro about 6 years ago for depression and anxiety - not expecting it to do anything for my IC. Turns out it helped both of the mental health issues AND took away the last bit of urethral discomfort I'd been having. I never had "pain", so to speak, so I am not sure if it would help with that or not.

I don't think SSRIs are typically prescribed for IC pain. Usually you hear about Elavil being used for that purpose. I'm sorry you had a bad experience with that medication.
__________________
Kim

Diagnosed August 2001

Current IC meds: Elmiron (since 2001), Levaquin (one pill after intercourse to prevent UTIs), Lexapro (since 2003 for depression & anxiety, but also helps my IC)


Past IC meds: Amitriptyline (Elavil), Hydroxyzine (Vistaril), Detrol LA (They all helped, but I was able to discontinue them.)

My IC story: http://www.ic-network.com/patientstories/kim.html It's very outdated now. I've been virtually symptom free and able to eat & drink whatever I'd like for several years now.

*****************************

“We who lived in concentration camps can remember the men who walked through the huts comforting others, giving away their last piece of bread. They may have been few in number, but they offer sufficient proof that everything can be taken from a man but one thing: the last of the human freedoms -- to choose one's attitude in any given set of circumstances, to choose one's own way.” ~ Viktor Frankl

“You cannot control what happens to you, but you can control your attitude toward what happens to you, and in that, you will be mastering change rather than allowing it to master you.” ~ Brian Tracy
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Old 11-12-2009, 08:15 AM   #7
lttlewun
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Hello everyone!

I thought I would jump in on this conversation since it has to do with Ativan. I take .5mg a couple of times a week and it realllly helps me. I don't have pain, but I have urethral/vaginal discomfort and burning/stinging when urinating. I don't know if that is still considered to be some type of pain. I occasionaly get frequency, but that does not happen very often (thank God). When I take the Ativan I either feel completely "normal" or almost "normal". I want to pop a pill every day, but I'm afraid of becoming dependent as I have read that Ativan can be very addicting. My Uro said I can take it up to 3x per week and I should not have a problem becoming dependent, but I want to take it everyday!

Does anyone know if there is another drug similar to Ativan that I can take on a daily basis that will give me the same relief? I have an appt. with my PCP tomorrow and was going to ask him about this.

Thanks all! Wishing everyone a pain-free day!
__________________
Diagnosed Sept. 2009 based on symptoms

Current Medications:

Elmiron 100 mg 3x per day (started Sept. 09)

Glucosamine w/MSM 1000 mg per day (started Oct. 2009) Added Glucosamine w/MSM and Chondroiton in Jan. 2010

Elavil 12 mg at bedtime (started Dec. 2009) Upped my dose to 25mg on Dec.14th) Lowered dose to 12 mg again on Dec. 28 due to the feeling that I was having slight retention

IC Diet

Ativan as needed .5 mg (this really seems to help with my symptoms)

Update as of Jan. 6th 2010


Stopping Elmiron and weaning off of Elavil

Started using 10 mg vaginal valium
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Old 11-12-2009, 09:47 AM   #8
Tuckersmom
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I take 0.5 mgs of xanex 3 times daily. Started out at 2 times per day, but eventually went to taking 3. My PCP prescribes it for me. Yes, it is physiologically addicting, but like my doctor said: if I was on insulin for Diabetes, or on high blood pressure meds, and they were addicting, would I not take them? He will wean me off slowly if I ever go off of them.
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Old 11-17-2009, 04:08 PM   #9
orchid53
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Have you tried Wellbutrin? Its an NDRI. You could also consider a low-dose of Effexor (SNRI) which also helps with anxiety. With all anti-depressants, its really a matter of trial and error, unfortunately. Like you said, Elavil worked except it increased heart rate, but nortriptyline which is in the same family made you wired...so expect to try a few different ones.
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Old 11-17-2009, 06:49 PM   #10
leelee88
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Quote:
Originally Posted by Tuckersmom View Post
I take 0.5 mgs of xanex 3 times daily. Started out at 2 times per day, but eventually went to taking 3. My PCP prescribes it for me. Yes, it is physiologically addicting, but like my doctor said: if I was on insulin for Diabetes, or on high blood pressure meds, and they were addicting, would I not take them? He will wean me off slowly if I ever go off of them.
I agree! I was very hesitant about taking Ativan because I was scared I would get addicted to them. But I have no choice the panic attacks were getting very bad to the point I could not drive.. Ativan also make me feel normal..I guess my anxiety levels are really high.. My Dr said she seen know problem with taking them because I needed them more than I needed the stress from the panic attacks.. They were taking so much out of me...
__________________
Hugs
Ronda

ONE Second, ONE Bite, ONE Breath, ONE Pill, ONE Minute, ONE Teardrop, ONE Hour, ONE Sip.. ONE DAY! I will Prevail from this disease! IC Hoping for a Cure!


Link to Patient Handbook:
http://www.ic-network.com/handbook/

Diet Reference Sheet:
http://www.ic-network.com/diet/icndi...tsheet0909.pdf

Meds For IC: Lyrica-25mg Glucosamine-500 MSM-500mg, Prosed Ds -When Flaring

Other Meds: Levlite- Continious Birtcontrol, Micardis-40mg for High Blood Pressure

Meds I have Tried:
Topamax,Tofranil, Elmiron, Atarax, Cymbalta, Elavil, Enablex, Detral La, Prydium.
Lexapro< Bad reaction to this med!
Intstills, could not continue them due to some kind of reaction after 3rd instill. Tasted the lidocaine in my mouth, tongue and lips went numb then went into what seemed like a panic attack. Shaking, racing heart, tingling face/head, blood pressure shot up..

Dx With IC in Nov 2006 with Hydro/Cysto
Hydro/Cysto Caused Bladder to Rupture.

Other Dxs-Vulvodynia,Fibro, Endo, IBS, HPV, Migraines, Spastic Colon, Mild Dysplasia.



ICN Volunteers are not medical authorities nor do we offer medical advice. In all cases, we strongly encourage you to discuss your medical treatment with your personal medical care provider. Only they can, and should, give medical recommendations to you.
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