Have you ever had Sanctura/Detrol/Ditropan cause Flares?

[MommaWuzzi]

I went to a urologist for the first time since IC diagnosis on Tuesday. He started me on Sanctura, which I took promptly the next morning. I noticed a slight uptick in symptoms that day, and shrugged it off to hangover from traveling (always makes me sicker). However, every day since I've had increased pain a few hours after taking it, and each day my symptoms have progressively worsened.

Now, it COULD be something else (i.e., I am mid-cycle, we did get unexpected company, the weather changed...), so I have continued to take this and assured myself I don't KNOW yet, and of course telling myself that this stuff is MADE for bladders, it really couldn't make my symptoms worse...

...could it?

Please let me know if you've ever had something like that cause increased symptoms.... Thanks!

[Briza]

Hi
I have IC and did not find any success at all with ditropan or dextrol. Luckily they did not cause me ANY side effects, just were not effective for my IC. Some experience the same as me, some experience retention with these meds, and even other IC patients find one of the OAB meds such as these to be most helpful! So yes, even for an IC bladder side effects such as retentioin or other side effects may occur, or the OAB med may not be helpful at all.

For sure...stress (both emotional and physical) can a play a huge part for most any IC patient in regards to their symptoms. It is so for me as I know it is for many others who post here!

One exprience I can share is that I and many of us here take certain meds in the evening, around dinnertime or so, to avoid the next day symptoms or morning groggies/hangover feeling. So possibly speaking to your dr and/or pharmacist would be helpful to see if it would be better to take Sanctura around dinnertime, or any med that causes sleepy or groggy side effects, to avoid that hangover feeling!

Hope this helps in anyway and wish you the best in your treatment!
B

[Zygala87]

Just my own experience: Detrol darn near did me in. The only medication as yet that threw me into a major flare. I would not touch it again with a ten foot pole! We all know our bodies are very much different so it may help others. Since you asked if anyone had trouble with this type of meds. I'm just putting in my two cents worth. Hugs, Ziggy

[ICNDonna]

I've never had a problem with sanctura, but it didn't help either.

Donna

[Tuckersmom]

I used Ditropan XL for several years, and am now on Enablex. Neither of them caused a flare, in fact, I would have to say they are the major reason (besides help from the good Lord!) that the IC is pretty much in control. My Uro told me to take them at night. Maybe try switching to a night time dose and see what happens.

[daisyj3]

I just posted something similar..I had my symptoms(frequency and urgency) worsen after taking vesicare and prosed ds on separate occasions. I actually think these meds make me worse, which is sad since they seem to help some people.

[MommaWuzzi]

The dosing on Sanctura is to take at morning on an empty stomach, then wait at least two hours to eat anything... that's why it can't be taken at night.

Why do you think taking it at night would change the pain and frequency? Just curious...

[LithEruiel]

I'm starting to wonder if Ditropan has been the cause of my problem. My doctor prescribed it in May and it seemed to help some but was also giving me PFD symptoms and stomach cramps. My doctor just upped my dose from 2x a day to 3x a day yesterday because I've been having a ton of frequency but then it started hurting a lot to pee. I stopped taking it altogether today and I'm having less pelvic pain and urination pain. I'm assuming it'll take some time to get completely out of my system. My frequency isn't better or worse.

[LithEruiel]

Does anyone know how long Ditropan stays in your system by the way?

[Tuckersmom]

Does anyone know how long Ditropan stays in your system by the way?

There's Ditropan XL that is in yor system for 24 hours. I don't know about plain Ditropan, but you could call and ask a pharmacist.

[daisyj3]

My doctor told me that since I had worsening of symptoms on Prosed and Vesicare that my problems lie more towards PFD. He said because when my bladder was relaxed by the meds it made my pelvic muscles react more which flared me and gave me cramps.

[LithEruiel]

Yeah, I am feeling so much better now that I've been of it for three days. I never had PFD symptoms before I was on Ditropan. I'll have to mention it to my doctor if I ever have the money to go back again...

[Landish]

My worst experience was with Detrol. I took it for only two days because the second day I got in the emergency room because I couldn’t urinate. They had to cath me.
I was at home and the flaring started after eating. I tried to urinate but nothing happened, I just pushed and pushed. It was the most painful experience ever, my bladder was full and I was off my mind, so I ran without my shoes and a robe to the car and fortunately the hospital was close to home.
The Administration guys didn’t help me immediately, they just watched me crying and telling my husband to fill up the paperwork. Only after filling up tons of questions they started to cath me. Then I had to pay $1000 for this wonderful service.
:shake:

[LithEruiel]

Oh how awful! It took about three months for me to get bad. I wonder why...just the build up in my system? I don't know. It seemed like it was working at first but I think it was probably placebo effect...

[Diamic65]

I try to take those meds and I could not pee. And they made me really tired. I hope they work for you.:smile tee DIAMIC65:toilet:

[Sarojini]

I tried Detrol, Ditropan, and the Oxytrol patch (basically Ditropan in patch form) back in 2004 right around the time I was diagnosed. All three made me retain urine and I had to cath myself to pee a number of times, so I quit taking them.

I haven't tried any of the newer medications in this class (Vesicare, Sanctura, etc), but because they all have similar mechanisms of action in the body, they can cause retention in people susceptible to it as well. Sometimes they don't cause complete retention (ie, being unable to urinate at all) - sometimes they can just cause incomplete emptying of the bladder, and if you have IC, that residual urine in there can be quite irritating. It'll cause that sensation that you have to pee again immediately after urinating, and it can cause pain as well. So yes, these meds can definitely cause a worsening of symptoms in some people with IC even though they are "made" for bladders.

[LithEruiel]

That's very interesting. I definitely felt like I was having retention too. I feel so much better now.