PurplePrincess
10-20-2006, 01:09 PM
After reading Dr. Theoharides Lecture on this site, about the IC Belly- He stated
A possible explanation is that the beginning of inflammation always involves what we call increased vascular permeability, which means that the blood vessels dilate and become leaky. The first thing that happens is that a lot of fluid comes out of the blood vessels and into the tissues. Then what happens is leukocytes/white blood cells come out and that might also set up inflammation. So, to the extent that the blood vessels become leaky, alot of fluid will come out and cause the "IC belly".
The dilation of the blood vessels doesn't last a long time. To the extent that we discussed earlier, nerve endings come to the different parts of the spinal cord. This will make different parts of the abdomen swell up. In this problem a drug like Atarax could possibly be helpful because the primarily molecule that causes the swelling is histamine. One of the more effective therapies for IC is the use of antithistamine, but it's a unique antihistamine - hydroxyzine (ATARAX OR VISTARIL).
Has anyone tried this? I am a very small girl- have always been under 110 my whole life- fast metabolism, anyways i cant gain weight for the life of me, but since ive had IC, i have the IC belly and im up to 116ish and its totally astonishing to me that i have this...
Do you all have IC belly stories/simliar situations, has anyone tried to diminish the IC belly by this method?
A possible explanation is that the beginning of inflammation always involves what we call increased vascular permeability, which means that the blood vessels dilate and become leaky. The first thing that happens is that a lot of fluid comes out of the blood vessels and into the tissues. Then what happens is leukocytes/white blood cells come out and that might also set up inflammation. So, to the extent that the blood vessels become leaky, alot of fluid will come out and cause the "IC belly".
The dilation of the blood vessels doesn't last a long time. To the extent that we discussed earlier, nerve endings come to the different parts of the spinal cord. This will make different parts of the abdomen swell up. In this problem a drug like Atarax could possibly be helpful because the primarily molecule that causes the swelling is histamine. One of the more effective therapies for IC is the use of antithistamine, but it's a unique antihistamine - hydroxyzine (ATARAX OR VISTARIL).
Has anyone tried this? I am a very small girl- have always been under 110 my whole life- fast metabolism, anyways i cant gain weight for the life of me, but since ive had IC, i have the IC belly and im up to 116ish and its totally astonishing to me that i have this...
Do you all have IC belly stories/simliar situations, has anyone tried to diminish the IC belly by this method?